ATIP / Avenir
IUH Saint-Louis, Inserm U944
Phone: +331 53 72 40 63
Alex Puissant is currently group leader of a young ATIP / AVENIR team created in January 2017 at the Institute of Hematology (IUH) at the Saint-Louis Hospital, in Paris (France).
After receiving his Ph.D. degree (2010) at the Mediterranean Center of Molecular Medecine (C3M) in Nice (France), Alex did his post-doctoral training at the Dana Farber Cancer Institute (DFCI/Harvard) in Boston (MA, USA), prior to joining Inserm in 2016.
His research is mainly focused on understanding mechanisms of progression and chemoresistance of a highly aggressive and deadly form of leukemia termed as Acute Myeloid Leukemias (AML). To do so, he has developed syngenic model of AML to set up screens using doxycycline-inducible shRNA libraries. He also performed long-term culture methods of primary leukemic blasts from patients with AML in order to identify cellular regulators of leukemic stem cell function.